ACER2 antibody (Middle Region)

Catalog No. ABIN2790349

Product Details anti-ACER2 Antibody

Target: ACER2 (Alkaline Ceramidase 2 (ACER2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACER2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DELAVLWVLM CALAMWFPRR YLPKIFRNDR GRFKVVVSVL SAVTTCLAFV

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against ACER2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human ACER2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 275 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ACER2

Target: ACER2 (Alkaline Ceramidase 2 (ACER2))

Alternative Name: ACER2 (ACER2 Products)

Synonyms: ASAH3L antibody, asah3l antibody, ALKCDase2 antibody, 2410116I05Rik antibody, Asah3l antibody, CRG-L1 antibody, maCER2 antibody, alkaline ceramidase 2 antibody, alkaline ceramidase 2 S homeolog antibody, ACER2 antibody, acer2.S antibody, acer2 antibody, Acer2 antibody

Background: The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine.
Alias Symbols: ASAH3L, FLJ41587
Protein Size: 275

Molecular Weight: 31 kDa

Gene ID: 340485

NCBI Accession: NM_001010887, NP_001010887

UniProt: Q5QJU3

Pathways: Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process