SYT8 antibody (C-Term)

Catalog No. ABIN2790347

Product Details anti-SYT8 Antibody

Target: SYT8 (Synaptotagmin VIII (SYT8))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYT8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LVSCLLCAAC CCCRRHRKKP RDKESVGLGS ARGTTTTHLV QPDVDGLESS

Predicted Reactivity: Cow: 79%, Dog: 85%, Human: 100%, Mouse: 79%, Pig: 93%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against SYT8. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human SYT8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SYT8

Target: SYT8 (Synaptotagmin VIII (SYT8))

Alternative Name: SYT8 (SYT8 Products)

Synonyms: synaptotagmin 8 antibody, synaptotagmin VIII antibody, SYT8 antibody, syt8 antibody, Syt8 antibody

Background: This gene encodes a member of the synaptotagmin protein family. Synaptotagmins are membrane proteins that are important in neurotransmission and hormone secretion, both of which involve regulated exocytosis. Expression of the encoded protein in human pancreatic islets has been connected to activity of the promoter for the insulin gene, on the same chromosome several hundred kilobases away (PMID: 21336277 and 22928559). This association would link response to gluclose to insulin secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.
Protein Size: 310

Molecular Weight: 34 kDa

Gene ID: 90019

NCBI Accession: NM_138567, NP_612634

UniProt: Q8NBV8