STXBP4 antibody (N-Term)

Catalog No. ABIN2790280

Product Details anti-STXBP4 Antibody

Target: STXBP4 (Syntaxin Binding Protein 4 (STXBP4))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STXBP4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SVNKESMIGV SFEEAKSIIT GAKLRLESAW EIAFIRQKSD NIQPENLSCT

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against STXBP4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human STXBP4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 553 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for STXBP4

Target: STXBP4 (Syntaxin Binding Protein 4 (STXBP4))

Alternative Name: STXBP4 (STXBP4 Products)

Synonyms: STXBP4 antibody, LOC733742 antibody, MGC131203 antibody, DKFZp468L076 antibody, Synip antibody, 6030470M02Rik antibody, syntaxin binding protein 4 antibody, syntaxin binding protein 4 L homeolog antibody, STXBP4 antibody, stxbp4 antibody, stxbp4.L antibody, Stxbp4 antibody

Background: STXBP4 plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. STXBP4 inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. STXBP4 may also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
Alias Symbols: FLJ16496, MGC149829, MGC50337, Synip
Protein Interaction Partner: KLHL42, LATS2, ATN1, UBC, Plk1, STX4,
Protein Size: 553

Molecular Weight: 62 kDa

Gene ID: 252983

NCBI Accession: NM_178509, NP_848604

UniProt: Q6ZWJ1