ARPC1B antibody (Middle Region)
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- Target See all ARPC1B Antibodies
- ARPC1B (Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ARPC1B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KKPIRSTVLS LDWHPNNVLL AAGSCDFKCR IFSAYIKEVE ERPAPTPWGS
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against ARPC1B. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human ARPC1B
- Top Product
- Discover our top product ARPC1B Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 372 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ARPC1B (Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B))
- Alternative Name
- ARPC1B (ARPC1B Products)
- Synonyms
- ARC41 antibody, p40-ARC antibody, p41-ARC antibody, cb871 antibody, arpc1a antibody, fj15h02 antibody, zgc:64056 antibody, wu:fj08e12 antibody, wu:fj15h02 antibody, 41kDa antibody, AA408064 antibody, AA408534 antibody, AA571392 antibody, AF007010 antibody, AW208418 antibody, L72 antibody, SOP2Hs antibody, ACTIN-RELATED PROTEIN C1 antibody, ARPC1 antibody, F16D14.14 antibody, F16D14_14 antibody, actin-related protein C1B antibody, arc41 antibody, p40-arc antibody, p41-arc antibody, actin related protein 2/3 complex subunit 1B antibody, actin related protein 2/3 complex, subunit 1B antibody, ARP2/3 complex 41 kDa subunit antibody, actin-related protein C1B antibody, actin-related protein 2/3 complex subunit 1B antibody, actin related protein 2/3 complex subunit 1B S homeolog antibody, ARPC1B antibody, Arpc1b antibody, EHI_094120 antibody, arpc1b antibody, LOC100410640 antibody, arpc1b.S antibody
- Background
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This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.
Alias Symbols: ARC41, p40-ARC, p41-ARC
Protein Interaction Partner: SUMO2, UBC, SUMO1, NEDD8, BTF3L4, C14orf142, IPO11, TPRKB, PDCD4, ANP32B, ARPC2, ACTR2, ACTR3, ARPC3, ARPC4, ARPC5, TOM1L1, ANP32A, VBP1, UBE3A, TPD52L2, TPD52, RPA2, RANGAP1, PRKACB, PPP2R5D, METTL1, HSF1, DR1, DHPS, CALU, CALR, AARS, SRPK2, PAN2, WASL,
Protein Size: 372 - Molecular Weight
- 41 kDa
- Gene ID
- 10095
- NCBI Accession
- NM_005720, NP_005711
- UniProt
- O15143
- Pathways
- RTK Signaling, Regulation of Actin Filament Polymerization
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