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NANS antibody (C-Term)

NANS Reactivity: Human, Rat, Cow, Dog, Rabbit, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2790121
  • Target See all NANS Antibodies
    NANS (N-Acetylneuraminic Acid Synthase (NANS))
    Binding Specificity
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 26
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Cow, Dog, Rabbit, Pig
    Host
    • 19
    • 7
    Rabbit
    Clonality
    • 20
    • 6
    Polyclonal
    Conjugate
    • 17
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    This NANS antibody is un-conjugated
    Application
    • 16
    • 10
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    DMLTVKVGEP KGYPPEDIFN LVGKKVLVTV EEDDTIMEEL VDNHGKKIKS
    Predicted Reactivity
    Cow: 86%, Dog: 79%, Human: 100%, Pig: 86%, Rabbit: 79%, Rat: 86%
    Characteristics
    This is a rabbit polyclonal antibody against NANS. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product NANS Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 359 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NANS (N-Acetylneuraminic Acid Synthase (NANS))
    Alternative Name
    NANS (NANS Products)
    Synonyms
    MGC84329 antibody, SAS antibody, N-acetylneuraminate synthase L homeolog antibody, N-acetylneuraminate synthase antibody, nans.L antibody, NANS antibody, Nans antibody
    Background
    This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively, however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.
    Alias Symbols: SAS
    Protein Interaction Partner: SUMO2, UBC, NEDD8, ATG3, SMEK2, CNDP2, POLE3, DAK, NPEPPS, SLC9A3R1, RPLP2, MVD, PDIA3, GBP2, EIF4E, CKB, ASS1, BAG3, HSP90AB1, HSP90AA1, PCMT1, CRK, RAD23B, DDA1,
    Protein Size: 359
    Molecular Weight
    40 kDa
    Gene ID
    54187
    NCBI Accession
    NM_018946, NP_061819
    UniProt
    Q9NR45
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