NANS antibody (C-Term)
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- Target See all NANS Antibodies
- NANS (N-Acetylneuraminic Acid Synthase (NANS))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Cow, Dog, Rabbit, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NANS antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- DMLTVKVGEP KGYPPEDIFN LVGKKVLVTV EEDDTIMEEL VDNHGKKIKS
- Predicted Reactivity
- Cow: 86%, Dog: 79%, Human: 100%, Pig: 86%, Rabbit: 79%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against NANS. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product NANS Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 359 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NANS (N-Acetylneuraminic Acid Synthase (NANS))
- Alternative Name
- NANS (NANS Products)
- Synonyms
- MGC84329 antibody, SAS antibody, N-acetylneuraminate synthase L homeolog antibody, N-acetylneuraminate synthase antibody, nans.L antibody, NANS antibody, Nans antibody
- Background
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This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively, however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.
Alias Symbols: SAS
Protein Interaction Partner: SUMO2, UBC, NEDD8, ATG3, SMEK2, CNDP2, POLE3, DAK, NPEPPS, SLC9A3R1, RPLP2, MVD, PDIA3, GBP2, EIF4E, CKB, ASS1, BAG3, HSP90AB1, HSP90AA1, PCMT1, CRK, RAD23B, DDA1,
Protein Size: 359 - Molecular Weight
- 40 kDa
- Gene ID
- 54187
- NCBI Accession
- NM_018946, NP_061819
- UniProt
- Q9NR45
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