SEC61A1 antibody (C-Term)

Catalog No. ABIN2790091

Product Details anti-SEC61A1 Antibody

Target: SEC61A1 (Sec61 alpha 1 Subunit (SEC61A1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Horse, Rabbit, Guinea Pig, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC61A1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TWIEVSGSSA KDVAKQLKEQ QMVMRGHRET SMVHELNRYI PTAAAFGGLC

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SEC61A1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SEC61A1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 476 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SEC61A1

Target: SEC61A1 (Sec61 alpha 1 Subunit (SEC61A1))

Alternative Name: SEC61A1 (SEC61A1 Products)

Synonyms: HSEC61 antibody, SEC61 antibody, SEC61A antibody, AA408394 antibody, AA410007 antibody, Sec61a antibody, sec61 antibody, sec61a antibody, sec61alpha antibody, SEC61A1 antibody, secY1 antibody, chunp6898 antibody, fb62c11 antibody, sec61al1 antibody, wu:fb62c11 antibody, Sec61 translocon alpha 1 subunit antibody, Sec61 alpha 1 subunit (S. cerevisiae) antibody, Sec61 translocon alpha 1 subunit S homeolog antibody, preprotein translocase subunit SecY antibody, Sec61 alpha 1 subunit antibody, translocon subunit antibody, translocon alpha subunit Sec61 antibody, SEC61A1 antibody, Sec61a1 antibody, sec61a1.S antibody, sec61a1 antibody, HVO_RS16965 antibody, SEC61 antibody, sec61 antibody

Background: The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits.
Alias Symbols: HSEC61, SEC61, SEC61A
Protein Interaction Partner: UBC, EGFR, STAU1, ADRB2, ILK, CLN5, CLN3, env, MLH1, HSPA5, CFTR, MDC1, SEC61B, OPRD1, CALM1, BCAP31, BAG6, HLA-A, PDIA3, ASNA1, SUMO2, TMEM173, USP19, USP11, SERP1, SEC61A1, APOB, NDN, AP1S1,
Protein Size: 476

Molecular Weight: 52 kDa

Gene ID: 29927

NCBI Accession: NM_013336, NP_037468

UniProt: P61619