Retinoic Acid Early Transcript 1E (RAET1E) (C-Term) antibody
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- Target See all Retinoic Acid Early Transcript 1E (RAET1E) Antibodies
- Retinoic Acid Early Transcript 1E (RAET1E)
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LEKYFRKLSK GDCDHWLREF LGHWEAMPEP TVSPVNASDI HWSSSSLPDR
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against RAET1E. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human RAET1E
- Top Product
- Discover our top product RAET1E Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 263 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Retinoic Acid Early Transcript 1E (RAET1E)
- Alternative Name
- RAET1E (RAET1E Products)
- Synonyms
- LETAL antibody, N2DL-4 antibody, NKG2DL4 antibody, RAET1E2 antibody, RL-4 antibody, ULBP4 antibody, bA350J20.7 antibody, retinoic acid early transcript 1E antibody, RAET1E antibody, Raet1e antibody
- Background
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This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: LETAL, MGC125308, MGC125309, RAET1E2, ULBP4, bA350J20.7
Protein Interaction Partner: KLRK1, RAET1E,
Protein Size: 263 - Molecular Weight
- 27 kDa
- Gene ID
- 135250
- NCBI Accession
- NM_139165, NP_631904
- UniProt
- Q8TD07
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