CFHR4 antibody (C-Term)
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- Target See all CFHR4 Antibodies
- CFHR4 (Complement Factor H-Related 4 (CFHR4))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CFHR4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- SNGEWSEPPR CIHPCIITEE NMNKNNIQLK GKSDIKYYAK TGDTIEFMCK
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against CFHR4. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product CFHR4 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 577 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CFHR4 (Complement Factor H-Related 4 (CFHR4))
- Alternative Name
- CFHR4 (CFHR4 Products)
- Synonyms
- CFHL4 antibody, FHR-4 antibody, FHR4 antibody, complement factor H related 4 antibody, CFHR4 antibody
- Background
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This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene.
Alias Symbols: CFHL4, FHR-4, FHR4, RP4-608O15.2
Protein Interaction Partner: CDC42, CFHR4, C3,
Protein Size: 577 - Molecular Weight
- 63 kDa
- Gene ID
- 10877
- NCBI Accession
- NM_001201551, NP_001188480
- UniProt
- A8K9N7
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