PDE6G antibody (N-Term)

Catalog No. ABIN2790053

Product Details anti-PDE6G Antibody

Target: PDE6G (phosphodiesterase 6G, CGMP-Specific, Rod, gamma (PDE6G))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE6G antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GPVTPRKGPP KFKQRQTRQF KSKPPKKGVQ GFGDDIPGME GLGTDITVIC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PDE6G. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 87 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDE6G

Target: PDE6G (phosphodiesterase 6G, CGMP-Specific, Rod, gamma (PDE6G))

Alternative Name: PDE6G (PDE6G Products)

Synonyms: PDEG antibody, RP57 antibody, Pdeg antibody, p3AT antibody, pde6g antibody, GMP-PDE gamma antibody, pde6g-a antibody, pde6g-b antibody, pde6g.S antibody, pde6gb antibody, pdeg antibody, phosphodiesterase 6G antibody, phosphodiesterase 6G, cGMP-specific, rod, gamma antibody, phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b antibody, phosphodiesterase 6G L homeolog antibody, PDE6G antibody, Pde6g antibody, pde6gb antibody, pde6g.L antibody

Background: This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants.
Alias Symbols: DKFZp686C0587, MGC125749, PDEG
Protein Interaction Partner: L3MBTL3, BHLHE40, FNBP1, PDE6G, TRIP10, DNM2, MAPK3, SRC, GNAO1, ADRBK1, GRB2,
Protein Size: 87

Molecular Weight: 10 kDa

Gene ID: 5148

NCBI Accession: NM_002602, NP_002593

UniProt: P18545

Pathways: EGFR Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction