REPS2 antibody (C-Term)

Catalog No. ABIN2790025

Product Details anti-REPS2 Antibody

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Pig, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REPS2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KDVLYSQPPS KPIRRKFRPE NQATENQEPS TAASGPASAA TMKPHPTVQK

Predicted Reactivity: Cow: 100%, Dog: 80%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 83%, Pig: 100%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against REPS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human REPS2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for REPS2

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Alternative Name: REPS2 (REPS2 Products)

Synonyms: POB1 antibody, RALBP1 associated Eps domain containing 2 antibody, RALBP1 associated Eps domain containing protein 2 antibody, REPS2 antibody, Reps2 antibody

Background: The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: EPN1, CDK1, AP2A1, GRB2, AMPH, AR, CDK5RAP2, REPS1, RALBP1, EPS15, ASAP1, ASAP2, PXN, RALB, RELA,
Protein Size: 521

Molecular Weight: 57 kDa

Gene ID: 9185

Pathways: EGFR Signaling Pathway