CRYGA antibody (N-Term)
CRYGA
Reactivity: Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse
WB
Host: Rabbit
Polyclonal
unconjugated
1 image
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- Target See all CRYGA products
- CRYGA (Crystallin, gamma A (CRYGA))
- Binding Specificity
- N-Term
- Reactivity
- Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CRYGA antibody is un-conjugated
- Application
- Western Blotting (WB)
- Sequence
- SIRVDSGCWM LYERPNYQGH QYFLRRGKYP DYQHWMGLSD SVQSCRIIPH
- Predicted Reactivity
- Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 79%, Zebrafish: 82%
- Characteristics
- This is a rabbit polyclonal antibody against CRYGA. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human CRYGA
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 174 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CRYGA (Crystallin, gamma A (CRYGA))
- Alternative Name
- CRYGA (CRYGA Products)
- Synonyms
- CRY-g-A antibody, CRYG1 antibody, CRYG5 antibody, Cryg-4 antibody, DGcry-4 antibody, cryg1 antibody, cryg5 antibody, MGC85425 antibody, CRYGA antibody, crystallin gamma A antibody, crystallin, gamma A antibody, crystallin gamma A L homeolog antibody, gamma-crystallin A antibody, CRYGA antibody, Cryga antibody, cryga.L antibody, LOC100630282 antibody, LOC100355936 antibody
- Background
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Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.
Alias Symbols: CRY-g-A, CRYG1, CRYG5
Protein Interaction Partner: TRAF1,
Protein Size: 174 - Molecular Weight
- 21 kDa
- Gene ID
- 1418
- NCBI Accession
- NM_014617, NP_055432
- UniProt
- P11844
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