HBG2 antibody (Middle Region)

Catalog No. ABIN2789939

Product Details anti-HBG2 Antibody

Target: HBG2 (Hemoglobin, gamma G (HBG2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit, Rat, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBG2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MGNPKVKAHG KKVLTSLGDA IKHLDDLKGT FAQLSELHCD KLHVDPENFK

Predicted Reactivity: Cow: 100%, Dog: 77%, Goat: 100%, Guinea Pig: 77%, Horse: 77%, Human: 100%, Mouse: 83%, Pig: 93%, Rabbit: 75%, Rat: 83%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against HBG2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 147 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HBG2

Target: HBG2 (Hemoglobin, gamma G (HBG2))

Alternative Name: HBG2 (HBG2 Products)

Synonyms: TNCY antibody, hbb2 antibody, MGC88976 antibody, HBG antibody, hemoglobin subunit gamma 2 antibody, hemoglobin subunit gamma 2 L homeolog antibody, hemoglobin, gamma G antibody, hemoglobin subunit gamma 2 S homeolog antibody, HBG2 antibody, hbg2 antibody, hbg2.L antibody, hbg2.S antibody

Background: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Alias Symbols: FLJ76540
Protein Interaction Partner: VCAM1, SMAD5, RPSA, ITGA4, APP, CYB5R3, HBG2, HBB,
Protein Size: 147

Molecular Weight: 16 kDa

Gene ID: 3048

NCBI Accession: NM_000184, NP_000175

UniProt: P69892