GPR68 antibody (Middle Region)
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- Target See all GPR68 Antibodies
- GPR68 (G Protein-Coupled Receptor 68 (GPR68))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Horse, Rabbit, Dog, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GPR68 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- SIYFLMHEEV IEDENQHRVC FEHYPIQAWQ RAINYYRFLV GFLFPICLLL
- Predicted Reactivity
- Dog: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 79%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against GPR68. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human GPR68
- Top Product
- Discover our top product GPR68 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 365 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GPR68 (G Protein-Coupled Receptor 68 (GPR68))
- Alternative Name
- GPR68 (GPR68 Products)
- Synonyms
- GPR68 antibody, GPR12A antibody, OGR1 antibody, BB131428 antibody, Ogr1 antibody, G protein-coupled receptor 68 antibody, GPR68 antibody, LOC100348269 antibody, Gpr68 antibody
- Background
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Proton-sensing receptor is involved in pH homeostasis. GPR68 may represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. GPR68 mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer.
Alias Symbols: MGC111379, MGC156983, OGR1, GPR12A
Protein Size: 365 - Molecular Weight
- 41 kDa
- Gene ID
- 8111
- NCBI Accession
- NM_003485, NP_003476
- UniProt
- Q15743
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