SYNGAP1 antibody (C-Term)

Catalog No. ABIN2789829

Product Details anti-SYNGAP1 Antibody

Target: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYNGAP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EYKLKEYSKS MDESRLDRVK EYEEEIHSLK ERLHMSNRKL EEYERRLLSQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against SYNGAP1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1343 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SYNGAP1

Target: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Alternative Name: SYNGAP1 (SYNGAP1 Products)

Synonyms: SYNGAP1 antibody, Syngap antibody, MRD5 antibody, RASA1 antibody, RASA5 antibody, SYNGAP antibody, Gm1963 antibody, synaptic Ras GTPase activating protein 1 antibody, zinc finger and BTB domain containing 9 antibody, synaptic Ras GTPase activating protein 1 homolog (rat) antibody, SYNGAP1 antibody, ZBTB9 antibody, syngap1 antibody, Syngap1 antibody

Background: The protein encoded by this gene is a major component of the postsynaptic density (PSD), a group of proteins found associated with NMDA receptors at synapses. The encoded protein is phosphorylated by calmodulin-dependent protein kinase II and dephosphorylated by NMDA receptor activation. Defects in this gene are a cause of mental retardation autosomal dominant type 5 (MRD5).
Alias Symbols: DKFZp761G1421, KIAA1938, MRD5, RASA1, RASA5, SYNGAP
Protein Interaction Partner: SAAL1, DLGAP4, GRIN1, ULK1, ULK2, MPDZ, CAMK2A, TRIP6, DLG4, GRIN2D, DLG3, KDR, PDGFRB, GRIN2B,
Protein Size: 1343

Molecular Weight: 148 kDa

Gene ID: 8831

NCBI Accession: NM_006772, NP_006763

UniProt: Q96PV0

Pathways: Regulation of long-term Neuronal Synaptic Plasticity