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SYNGAP1 antibody (C-Term)

SYNGAP1 Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Horse, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2789829
  • Target See all SYNGAP1 Antibodies
    SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
    Binding Specificity
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Pig, Horse, Rabbit, Zebrafish (Danio rerio)
    Host
    • 19
    • 2
    Rabbit
    Clonality
    • 18
    • 3
    Polyclonal
    Conjugate
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SYNGAP1 antibody is un-conjugated
    Application
    • 10
    • 8
    • 5
    • 2
    • 2
    Western Blotting (WB)
    Sequence
    EYKLKEYSKS MDESRLDRVK EYEEEIHSLK ERLHMSNRKL EEYERRLLSQ
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against SYNGAP1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product SYNGAP1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1343 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
    Alternative Name
    SYNGAP1 (SYNGAP1 Products)
    Synonyms
    SYNGAP1 antibody, Syngap antibody, MRD5 antibody, RASA1 antibody, RASA5 antibody, SYNGAP antibody, Gm1963 antibody, synaptic Ras GTPase activating protein 1 antibody, zinc finger and BTB domain containing 9 antibody, synaptic Ras GTPase activating protein 1 homolog (rat) antibody, SYNGAP1 antibody, ZBTB9 antibody, syngap1 antibody, Syngap1 antibody
    Background
    The protein encoded by this gene is a major component of the postsynaptic density (PSD), a group of proteins found associated with NMDA receptors at synapses. The encoded protein is phosphorylated by calmodulin-dependent protein kinase II and dephosphorylated by NMDA receptor activation. Defects in this gene are a cause of mental retardation autosomal dominant type 5 (MRD5).
    Alias Symbols: DKFZp761G1421, KIAA1938, MRD5, RASA1, RASA5, SYNGAP
    Protein Interaction Partner: SAAL1, DLGAP4, GRIN1, ULK1, ULK2, MPDZ, CAMK2A, TRIP6, DLG4, GRIN2D, DLG3, KDR, PDGFRB, GRIN2B,
    Protein Size: 1343
    Molecular Weight
    148 kDa
    Gene ID
    8831
    NCBI Accession
    NM_006772, NP_006763
    UniProt
    Q96PV0
    Pathways
    Regulation of long-term Neuronal Synaptic Plasticity
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