ORC5 antibody (C-Term)

Catalog No. ABIN2789793

Product Details anti-ORC5 Antibody

Target: ORC5 (Origin Recognition Complex, Subunit 5 (ORC5))

Binding Specificity: C-Term

Reactivity: Mouse, Human, Rat, Cow, Pig, Rabbit, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TRKLWRNIEP HLKKAMQTVY LREISSSQWE KLQKDDTDPG QLKGIRGSIE

Predicted Reactivity: Cow: 100%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ORC5. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 324 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ORC5

Target: ORC5 (Origin Recognition Complex, Subunit 5 (ORC5))

Alternative Name: ORC5 (ORC5 Products)

Background: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: ORC5, ORC5P, ORC5T
Protein Interaction Partner: NIF3L1, ORC4, ORC2, ORC1, NONO, MCM5, MCM3, MCM2, LAMB2, KRT18, CDC6, CDC5L, DMRTA1, SIPA1L2, UBQLN4, TXNDC11, PPP1CA, ORC3, STAB1, CALCOCO2, TAX1BP1, CDC45, CDC7, UBC, LRWD1, DGKA, UBD, tat, MCM7, ORC6, DBF4, RPA2, ORC5, MCM4,
Protein Size: 324

Molecular Weight: 37 kDa

Gene ID: 5001

NCBI Accession: NM_181747, NP_859531

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA