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IL-19 antibody (C-Term)
IL19
Reactivity: Human, Rat, Mouse, Dog, Cow, Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IL-19 Antibody
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Target
See all IL-19 (IL19) Antibodies
IL-19 (IL19)
(Interleukin 19 (IL19))
Binding Specificity
All epitopes for IL-19 antibodies
C-Term
Reactivity
Human, Rat, Mouse, Dog, Cow, Pig
Host
All hosts for IL-19 antibodies
Rabbit
Clonality
All clonalities for IL-19 antibodies
Polyclonal
Conjugate
All conjugates for IL-19 antibodies
This IL-19 antibody is un-conjugated
Application
All applications for IL-19 antibodies
Western Blotting (WB)
Sequence
KILRKISSIA NSFLYMQKTL RQCQEQRQCH CRQEATNATR VIHDNYDQLE
Predicted Reactivity
Cow: 93%, Dog: 79%, Human: 100%, Mouse: 85%, Pig: 93%, Rat: 86%
Characteristics
This is a rabbit polyclonal antibody against IL19. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human IL19
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for IL-19
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Target
IL-19 (IL19)
(Interleukin 19 (IL19))
Alternative Name
IL19 (IL19 Products )
Synonyms
IL-10C antibody, MDA1 antibody, NG.1 antibody, ZMDA1 antibody, IL19 antibody, interleukin 19 antibody, IL19 antibody, Il19 antibody
Background
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. Alias Symbols: IL-10C, MDA1, NG.1, ZMDA1 Protein Interaction Partner: IL20RA, Protein Size: 215
Molecular Weight
23 kDa
Gene ID
29949
NCBI Accession
NM_153758 , NP_715639
UniProt
Q5VUT3
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