IL-19 antibody (Middle Region)

Catalog No. ABIN2789718

Product Details anti-IL-19 Antibody

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Dog, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-19 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ILSTLETLQI IKPLDVCCVT KNLLAFYVDR VFKDHQEPNP KILRKISSIA

Predicted Reactivity: Cow: 79%, Dog: 86%, Human: 100%, Rabbit: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against IL19. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 215 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IL-19

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Alternative Name: IL19 (IL19 Products)

Synonyms: IL-10C antibody, MDA1 antibody, NG.1 antibody, ZMDA1 antibody, IL19 antibody, interleukin 19 antibody, IL19 antibody, Il19 antibody

Background: The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.
Alias Symbols: IL-10C, MDA1, NG.1, ZMDA1
Protein Interaction Partner: IL20RA,
Protein Size: 215

Molecular Weight: 18 kDa

Gene ID: 29949

NCBI Accession: NM_153758, NP_715639

UniProt: Q5VUT3