FGF20 antibody (C-Term)

Catalog No. ABIN2789708

Product Details anti-FGF20 Antibody

Target: FGF20 (Fibroblast Growth Factor 20 (FGF20))

Binding Specificity: C-Term

Reactivity: Mouse, Rat, Human, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Sheep, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF20 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IFREQFEENW YNTYSSNIYK HGDTGRRYFV ALNKDGTPRD GARSKRHQKF

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 77%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 77%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against FGF20. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 211 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FGF20

Target: FGF20 (Fibroblast Growth Factor 20 (FGF20))

Alternative Name: FGF20 (FGF20 Products)

Background: The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility.
Alias Symbols: FGF-20
Protein Interaction Partner: CTNNB1,
Protein Size: 211

Molecular Weight: 23 kDa

Gene ID: 26281

NCBI Accession: NM_019851, NP_062825

UniProt: Q9NP95

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway