LILRB2 antibody (C-Term)
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- Target See all LILRB2 Antibodies
- LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LILRB2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MDTRAAASEA PQDVTYAQLH SLTLRRKATE PPPSQEREPP AEPSIYATLA
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against LILRB2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product LILRB2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 598 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
- Alternative Name
- LILRB2 (LILRB2 Products)
- Synonyms
- CD85D antibody, ILT-4 antibody, ILT4 antibody, LIR-2 antibody, LIR2 antibody, MIR-10 antibody, MIR10 antibody, leukocyte immunoglobulin-like receptor subfamily A member 3 antibody, leukocyte immunoglobulin like receptor B2 antibody, LOC100433990 antibody, LILRB2 antibody
- Background
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This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD85D, ILT4, LILRA6, LIR-2, LIR2, MIR-10, MIR10
Protein Interaction Partner: PTPN6, FCGR1A, HLA-F, HLA-G, HLA-C, HLA-B, HLA-A,
Protein Size: 598 - Molecular Weight
- 65 kDa
- Gene ID
- 10288
- NCBI Accession
- NM_005874, NP_005865
- UniProt
- Q8N423
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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