RP9 antibody (C-Term)

Catalog No. ABIN2789660

Product Details anti-RP9 Antibody

Target: RP9 (Retinitis Pigmentosa 9 (Autosomal Dominant) (RP9))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Pig, Rat, Cow, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RP9 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DRSSSSSSEG KEKHKKKKKK EKHKKRKKEK KKKKKRKHKS SKSNEGSDSE

Predicted Reactivity: Cow: 92%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 93%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against RP9. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 221 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RP9

Target: RP9 (Retinitis Pigmentosa 9 (Autosomal Dominant) (RP9))

Alternative Name: RP9 (RP9 Products)

Synonyms: PAP-1 antibody, im:7137386 antibody, zgc:103448 antibody, MGC154533 antibody, Rp9h antibody, RP9, pre-mRNA splicing factor antibody, retinitis pigmentosa 9 (autosomal dominant) antibody, retinitis pigmentosa 9 (autosomal dominant)-like antibody, retinitis pigmentosa 9 (autosomal dominant) L homeolog antibody, retinitis pigmentosa 9 (human) antibody, RP9 antibody, LOC475279 antibody, rp9 antibody, rp9.L antibody, Rp9 antibody

Background: The protein encoded by this gene can be bound and phosphorylated by the protooncogene PIM1 product, a serine/threonine protein kinase . This protein localizes in nuclear speckles containing the splicing factors, and has a role in pre-mRNA splicing. CBF1-interacting protein (CIR), a corepressor of CBF1, can also bind to this protein and effects alternative splicing. Mutations in this gene result in autosomal dominant retinitis pigmentosa-9. This gene has a pseudogene (GeneID: 441212), which is located in tandem array approximately 166 kb distal to this gene.
Alias Symbols: PAP-1
Protein Interaction Partner: CIR1, APP, SUMO2, U2AF1,
Protein Size: 221

Molecular Weight: 26 kDa

Gene ID: 6100

NCBI Accession: NM_203288, NP_976033

UniProt: Q8TA86