HSPA1B antibody (C-Term)

Catalog No. ABIN2789650

Product Details anti-HSPA1B Antibody

Target: HSPA1B (Heat Shock 70kDa Protein 1B (HSPA1B))

Binding Specificity: C-Term

Reactivity: Mouse, Cow, Human, Rat, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPA1B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DKSTGKANKI TITNDKGRLS KEEIERMVQE AEKYKAEDEV QRERVSAKNA

Predicted Reactivity: Cow: 100%, Dog: 93%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Sheep: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against HSPA1B. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 641 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HSPA1B

Target: HSPA1B (Heat Shock 70kDa Protein 1B (HSPA1B))

Alternative Name: HSPA1B (HSPA1B Products)

Background: This intronless gene encodes a 70 kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
Alias Symbols: FLJ54328, HSP70-1B, HSP70-2, HSPA1A
Protein Interaction Partner: PA2G4, STUB1, UBC, TP53, BAG4, STAU1, TRIM25, RNF2, EZH2, FBXO6, PINK1, UBD, ADRB2, UBL4A, VCAM1, TGM2, PPP5C, ITGA4, HSP90AA1, FN1, DAB2, SMURF1, CTNNB1, FMNL1, UBASH3B, SHC1, PIK3R2, INPPL1, GRB2, EPS15, CRK, AP2M1, CBL, HSPBP1, CAND1, DCUN1D1, COPS5, C
Protein Size: 641

Molecular Weight: 70 kDa

Gene ID: 3304

NCBI Accession: NM_005346, NP_005337

UniProt: P08107