Ephrin B3 antibody (C-Term)
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- Target See all Ephrin B3 (EFNB3) Antibodies
- Ephrin B3 (EFNB3)
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Binding Specificity
- C-Term
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Reactivity
- Mouse, Human, Rat, Cow, Rabbit, Dog, Horse, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Ephrin B3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- AGAGGAMCWR RRRAKPSESR HPGPGSFGRG GSLGLGGGGG MGPREAEPGE
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against Efnb3. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Efnb3
- Top Product
- Discover our top product EFNB3 Primary Antibody
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Ephrin B3 (EFNB3)
- Alternative Name
- Efnb3 (EFNB3 Products)
- Synonyms
- efnb3-A antibody, EphB3 antibody, EFNB3 antibody, efnb3 antibody, id:ibd5049 antibody, zgc:111938 antibody, EFL-6 antibody, ELF-3 antibody, Elk-L3 antibody, Epl8 antibody, LERK-8 antibody, NLERK-2 antibody, ELK-L3 antibody, RGD1565678 antibody, EFL6 antibody, EPLG8 antibody, LERK8 antibody, ephrin B3 antibody, ephrin-B3 L homeolog antibody, ephrin-B3b antibody, ephrin-B3 antibody, EFNB3 antibody, efnb3.L antibody, efnb3b antibody, efnb3 antibody, Efnb3 antibody
- Background
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Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Efnb3 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. It may play a pivotal role in forebrain function. It binds to, and induce the collapse of, commissural axons/growth cones in vitro. Efnb3 may play a role in constraining the orientation of longitudinally projecting axons.
Alias Symbols: EFL-6, ELF-3, Elk-L3, Epl8, LERK-8, NLERK-2
Protein Size: 340 - Molecular Weight
- 36 kDa
- Gene ID
- 13643
- NCBI Accession
- NM_007911, NP_031937
- UniProt
- O35393
- Pathways
- RTK Signaling
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