CCT2 antibody (Middle Region)

Catalog No. ABIN2789485

Product Details anti-CCT2 Antibody

Target: CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish (Danio rerio), Rabbit, Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCT2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RVDSTAKVAE IEHAEKEKMK EKVERILKHG INCFINRQLI YNYPEQLFGA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CCT2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of CCT2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 535 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCT2

Target: CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))

Alternative Name: CCT2 (CCT2 Products)

Synonyms: fa26a01 antibody, fc58a11 antibody, CHUNP6883 antibody, wu:fa26a01 antibody, wu:fc58a11 antibody, cct2 antibody, MGC89448 antibody, CCT2 antibody, 99D8.1 antibody, CCT-beta antibody, CCTB antibody, PRO1633 antibody, TCP-1-beta antibody, Cctb antibody, chaperonin containing TCP1 subunit 2 antibody, chaperonin containing TCP1, subunit 2 (beta) antibody, chaperonin containing Tcp1, subunit 2 (beta) antibody, T-complex protein 1 subunit beta antibody, CCT2 antibody, cct2 antibody, Cct2 antibody, cct-2 antibody

Background: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin.
Alias Symbols: 99D8.1, CCT-beta, CCTB, MGC142074, MGC142076, PRO1633, TCP-1-beta
Protein Interaction Partner: SSSCA1, HUWE1, UBC, TP53, FUS, TUBG1, LGALS3BP, CDC20, NEDD1, STAU1, SUMO1, NEDD8, MDM2, WWOX, VRK2, CCT8, CCT7, IQGAP1, CCT6A, PRPF40A, CCT5, EEF1D, CCT3, PSMB8, FBXO6, FBXW4, NPM1, ILK, CDK5, CDK2, HDAC3, PAN2, US3, FAM86B2, METTL18, CAMKMT, METTL21B, V
Protein Size: 535

Molecular Weight: 59 kDa

Gene ID: 10576

NCBI Accession: NM_006431, NP_006422

UniProt: P78371