GP5 antibody (C-Term)
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- Target See all GP5 Antibodies
- GP5 (Glycoprotein V (Platelet) (GP5))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GP5 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PNSSEPWVWA QPVTTGKGQD HSPFWGFYFL LLAVQAMITV IIVFAMIKIG
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against GP5. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product GP5 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 560 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GP5 (Glycoprotein V (Platelet) (GP5))
- Alternative Name
- GP5 (GP5 Products)
- Synonyms
- lib antibody, GPV antibody, PLGPV antibody, CD42d antibody, glycoprotein V platelet L homeolog antibody, glycoprotein V platelet antibody, glycoprotein 5 (platelet) antibody, glycoprotein V (platelet) antibody, gp5.L antibody, GP5 antibody, Gp5 antibody
- Background
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Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain and a beta chain, that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome, a bleeding disorder.
Alias Symbols: CD42d
Protein Interaction Partner: YWHAZ, GP1BA, F2,
Protein Size: 560 - Molecular Weight
- 62 kDa
- Gene ID
- 2814
- NCBI Accession
- NM_004488, NP_004479
- UniProt
- P40197
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