TFPI antibody (Middle Region)
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- Target See all TFPI Antibodies
- TFPI (Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Rat, Mouse, Rabbit, Guinea Pig, Dog, Horse, Pig, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TFPI antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- QEKPDFCFLE EDPGICRGYI TRYFYNNQTK QCERFKYGGC LGNMNNFETL
- Predicted Reactivity
- Cow: 86%, Dog: 77%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against TFPI. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product TFPI Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 304 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TFPI (Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))
- Alternative Name
- TFPI (TFPI Products)
- Synonyms
- EPI antibody, LACI antibody, TFI antibody, TFPI1 antibody, A630013F22Rik antibody, AW552122 antibody, TFPI antibody, si:dz44f8.1 antibody, tfpib antibody, wu:fb92g01 antibody, zgc:152844 antibody, zgc:158592 antibody, tissue factor pathway inhibitor antibody, tissue factor pathway inhibitor a antibody, TFPI antibody, Tfpi antibody, tfpia antibody
- Background
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This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed.
Alias Symbols: EPI, LACI, TFI, TFPI1
Protein Interaction Partner: SMU1, SF3B1, BCAS2, SAP18, SRSF11, SON, SRSF7, APP, ELAVL1, PRSS3, MMP12, F10, THBS1, MMP7, ELANE, MMP9, MMP8, MMP1,
Protein Size: 304 - Molecular Weight
- 33 kDa
- Gene ID
- 7035
- NCBI Accession
- NM_006287, NP_006278
- UniProt
- P10646
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