TTLL3 antibody (C-Term)

Catalog No. ABIN2789303

Product Details anti-TTLL3 Antibody

Target: TTLL3 (Tubulin tyrosine Ligase-Like Family, Member 3 (TTLL3))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTLL3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: APVGRSRPKA NSRPDCDKPR AEACPMKRLS PLKPLPLVGT FQRRRGLGDM

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against TTLL3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of TTLL3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 434 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TTLL3

Target: TTLL3 (Tubulin tyrosine Ligase-Like Family, Member 3 (TTLL3))

Alternative Name: TTLL3 (TTLL3 Products)

Synonyms: HOTTL antibody, 4833441J24Rik antibody, AI450050 antibody, zgc:136840 antibody, tubulin tyrosine ligase like 3 antibody, tubulin tyrosine ligase-like family, member 3 antibody, Ttll3 antibody, TTLL3 antibody, ttll3 antibody

Background: TTLL3 is a monoglycylase which modifies alpha- and beta-tubulin, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin. It is involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. It is not involved in elongation step of the polyglycylation reaction.
Alias Symbols: DKFZp434B103, DKFZp686D076, FLJ13898, HOTTL, MGC120529, MGC120530, MGC120532
Protein Interaction Partner: CDCA5,
Protein Size: 434

Molecular Weight: 48 kDa

Gene ID: 26140

NCBI Accession: NM_001025930, NP_001021100

UniProt: Q9Y4R7