RASAL1 antibody (C-Term)
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- Target See all RASAL1 Antibodies
- RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RASAL1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- DTTLEADTGA CPEVLARQRA ATARLLEVLA DLDRAHEEFQ QQERGKAALG
- Predicted Reactivity
- Human: 100%, Pig: 83%
- Characteristics
- This is a rabbit polyclonal antibody against RASAL1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product RASAL1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 804 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))
- Alternative Name
- RASAL1 (RASAL1 Products)
- Synonyms
- RASAL1 antibody, rasal1 antibody, MGC79606 antibody, RASAL antibody, MRASAL antibody, RAS protein activator like 1 antibody, RAS protein activator like 1 (GAP1 like) antibody, RASAL1 antibody, rasal1 antibody, Rasal1 antibody
- Background
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The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.
Alias Symbols: RASAL
Protein Interaction Partner: RPS6KA3, NAPRT, RRAGB, UBC, PITX1,
Protein Size: 804 - Molecular Weight
- 88 kDa
- Gene ID
- 8437
- NCBI Accession
- NM_004658, NP_004649
- UniProt
- O95294
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