MRPL19 antibody (C-Term)

Catalog No. ABIN2789037

Product Details anti-MRPL19 Antibody

Target: MRPL19 (Mitochondrial Ribosomal Protein L19 (MRPL19))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL19 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PWSKRWERPN FNIKGIRFDL CLTEQQMKEA QKWNQPWLEF DMMREYDTSK

Predicted Reactivity: Cow: 86%, Dog: 79%, Horse: 79%, Human: 100%, Mouse: 92%, Pig: 79%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against MRPL19. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 292 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL19

Target: MRPL19 (Mitochondrial Ribosomal Protein L19 (MRPL19))

Alternative Name: MRPL19 (MRPL19 Products)

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
Alias Symbols: KIAA0104, L19mt, MGC20675, MRP-L15, MRP-L19, MRPL15, RLX1, RPML15
Protein Interaction Partner: TRIM63, TRIM55, UBC, NPM1, C1QBP, MRPL15, MRPL13, MRPL3, MATR3, APP, MRPL39, MRPL21, MRPL45, TMEM177, MRPL24, MRPL57, MRPL44, MRPL9, MRPL11, MRPL38, MRPL40, MRPL14, TSR1, NPLOC4, MRPL16, MRPL50, MAGEC1, CAND1, CUL1, CUL3, NEDD4L, NEDD4, ICT1,
Protein Size: 292

Molecular Weight: 33 kDa

Gene ID: 9801

NCBI Accession: NM_014763, NP_055578

UniProt: P49406