ARFGAP3 antibody (C-Term)
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- Target See all ARFGAP3 Antibodies
- ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Dog, Cow, Horse, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ARFGAP3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- SYWKKETSKD TETVLKTTGY SDRPTARRKP DYEPVENTDE AQKKFGNVKA
- Predicted Reactivity
- Cow: 86%, Dog: 100%, Horse: 93%, Human: 100%, Pig: 79%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against ARFGAP3. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product ARFGAP3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 516 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))
- Alternative Name
- ARFGAP3 (ARFGAP3 Products)
- Synonyms
- ARFGAP1 antibody, 0610009H19Rik antibody, 1810004P07Rik antibody, 1810035F16Rik antibody, 9130416J18Rik antibody, Arfgap1 antibody, arfgap1 antibody, xgap antibody, zgc:85765 antibody, arfgap3 antibody, ADP ribosylation factor GTPase activating protein 3 antibody, ADP-ribosylation factor GTPase activating protein 3 antibody, ADP ribosylation factor GTPase activating protein 3 S homeolog antibody, ARFGAP3 antibody, Arfgap3 antibody, arfgap3 antibody, arfgap3.S antibody
- Background
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The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.
Alias Symbols: ARFGAP1, FLJ45618
Protein Interaction Partner: UBC, CXCL8, CD14, APP, SMAD2,
Protein Size: 516 - Molecular Weight
- 57 kDa
- Gene ID
- 26286
- NCBI Accession
- NM_014570, NP_055385
- UniProt
- Q9NP61
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