DOK7 antibody (C-Term)
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- Target See all DOK7 Antibodies
- DOK7 (Docking Protein 7 (DOK7))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DOK7 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- RAHYDTPRSL CLAPRDHSPP SQGSPGNSAA RDSGGQTSAG CPSGWLGTRR
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against DOK7. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product DOK7 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 366 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- DOK7 (Docking Protein 7 (DOK7))
- Alternative Name
- DOK7 (DOK7 Products)
- Synonyms
- si:dkey-180b4.3 antibody, si:ch211-164d19.2 antibody, C4orf25 antibody, CMS1B antibody, A930013K19Rik antibody, AW049091 antibody, Dok-7 antibody, EF-12 antibody, Oit5 antibody, RGD1566416 antibody, dok-7 antibody, docking protein 7 antibody, DOK7 antibody, dok7 antibody, Dok7 antibody
- Background
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The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B.
Alias Symbols: C4orf25, CMS1B, FLJ33718, FLJ39137, FLJ90556
Protein Interaction Partner: Musk,
Protein Size: 366 - Molecular Weight
- 40 kDa
- Gene ID
- 285489
- NCBI Accession
- NM_173660, NP_775931
- Pathways
- Skeletal Muscle Fiber Development
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