VAC14 antibody (C-Term)

Catalog No. ABIN2788881

Product Details anti-VAC14 Antibody

Target: VAC14 (Vac14 Homolog (VAC14))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Rabbit, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAC14 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QLLSHRLQCV PNPELLQTED SLKAAPKSQK ADSPSIDYAE LLQHFEKVQN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 77%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 79%, Rabbit: 79%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against VAC14. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 781 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for VAC14

Target: VAC14 (Vac14 Homolog (VAC14))

Alternative Name: VAC14 (VAC14 Products)

Background: The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE and the PtdIns(3,5)P2 phosphatase FIG4. VAC14 functions as an activator of PIKFYVE.
Alias Symbols: ArPIKfyve, FLJ10305, FLJ36622, FLJ46582, MGC149815, MGC149816, TAX1BP2, TRX
Protein Interaction Partner: LINC00518, PIKFYVE, TCEANC, MGAT5B, C4orf33, PRR20A, PHYKPL, ACSS1, RHOXF2, PRADC1, ZNF34, LPAL2, ASB13, MTMR9, FNDC3B, NGB, SPRYD7, PELI1, PCMTD2, WDYHV1, PRR13, CD209, C11orf54, SMUG1, DDAH2, RBFOX2, SNF8, PDE4DIP, SIGLEC5, BHLHE40, TP53BP1, PPP2CA, PHF
Protein Size: 781

Molecular Weight: 86 kDa

Gene ID: 55697

NCBI Accession: NM_018052, NP_060522

UniProt: Q08AM6

Pathways: Inositol Metabolic Process