FAF1 antibody (Middle Region)

Catalog No. ABIN2788856

Product Details anti-FAF1 Antibody

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAF1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GLSYPCHRLT VGRRSSPAQT REQSEEQITD VHMVSDSDGD DFEDATEFGV

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FAF1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 650 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FAF1

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Alternative Name: FAF1 (FAF1 Products)

Synonyms: faf1 antibody, MGC53741 antibody, MGC80303 antibody, FAF1 antibody, zgc:55752 antibody, wu:fc25h12 antibody, HFAF1s antibody, UBXD12 antibody, UBXN3A antibody, hFAF1 antibody, AA408698 antibody, Dffrx antibody, Fam antibody, Fas (TNFRSF6) associated factor 1 S homeolog antibody, Fas (TNFRSF6) associated factor 1 L homeolog antibody, Fas associated factor 1 antibody, Fas (TNFRSF6) associated factor 1 antibody, Fas-associated factor 1 antibody, faf1.S antibody, faf1.L antibody, FAF1 antibody, faf1 antibody, Faf1 antibody

Background: Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain.
Alias Symbols: CGI-03, FLJ37524, HFAF1s, UBXD12, UBXN3A, hFAF1
Protein Interaction Partner: ASNA1, DDOST, GET4, FAF1, VAPA, VAPB, UBL4A, BAG6, VCP, UBC, RPN2, FAM114A1, SAMHD1, SWAP70, XPO7, PUF60, HSPH1, CARM1, SEC23A, PRMT3, FARSB, RANBP3, HIRIP3, HIST1H4A, SF1, UGP2, TLN1, TROVE2, SET, RPL24, PPP2R5C, PPM1G, PLOD2, ILK, HSPA4, GART, CARS, SKI
Protein Size: 650

Molecular Weight: 72 kDa

Gene ID: 11124

NCBI Accession: NM_007051, NP_008982

UniProt: Q9UNN5

Pathways: Maintenance of Protein Location