RPL7 antibody (C-Term)
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- Target See all RPL7 Antibodies
- RPL7 (Ribosomal Protein L7 (RPL7))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RPL7 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- YTVGKRFKEA NNFLWPFKLS SPRGGMKKKT THFVEGGDAG NREDQINRLI
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against RPL7. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product RPL7 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 248 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RPL7 (Ribosomal Protein L7 (RPL7))
- Alternative Name
- RPL7 (RPL7 Products)
- Synonyms
- BEST:GH04411 antibody, CG4897 antibody, Dmel\\CG4897 antibody, L7 antibody, RPL7 antibody, Rp L7 antibody, rpL7 antibody, rpl7 antibody, humL7-1 antibody, Rpl7a antibody, Surf-3 antibody, Ribosomal protein L7 antibody, 60S ribosomal protein L7 antibody, ribosomal protein L7 antibody, RpL7 antibody, rpl-7 antibody, RPL7 antibody, Rpl7 antibody
- Background
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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Alias Symbols: MGC117326, humL7-1, L7
Protein Interaction Partner: UBC, SUMO2, TUBGCP4, CEP250, TUBG1, TP53, STAU1, MDM2, LGR4, RPA3, RPA2, RPA1, RNF2, EED, PARK2, TARDBP, YWHAQ, PAN2, PHB, HSP90AB1, HSP90AA1, NOS2, IPO5, IL7R, FN1, ESR1, VCAM1, UBL4A, RAN, TRAF3IP1, EIF4A3, PPP1CC, MAGOH, HSP90AA5P, RPLP0P6, RPL10L, NIF
Protein Size: 248 - Molecular Weight
- 29 kDa
- Gene ID
- 6129
- NCBI Accession
- NM_000971, NP_000962
- UniProt
- P18124
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