MUS81 antibody (C-Term)

Catalog No. ABIN2788792

Product Details anti-MUS81 Antibody

Target: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUS81 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GETRGGGHRP ELLRELQRLH VTHTVRKLHV GDFVWVAQET NPRDPANPGE

Predicted Reactivity: Cow: 79%, Dog: 86%, Human: 100%, Mouse: 79%, Pig: 83%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against MUS81. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 551 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MUS81

Target: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Alternative Name: MUS81 (MUS81 Products)

Synonyms: CG3026 antibody, Dmel\\CG3026 antibody, EG:BACR7A4.16 antibody, MUS81 antibody, GB15332 antibody, ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81 antibody, ATMUS81 antibody, F6I18.220 antibody, F6I18_220 antibody, MMS AND UV SENSITIVE 81 antibody, SLX3 antibody, slx3 antibody, 1200008A18Rik antibody, AI182501 antibody, AW045863 antibody, wu:fc26g01 antibody, zgc:66489 antibody, zgc:91801 antibody, CG3026 gene product from transcript CG3026-RA antibody, MUS81 structure-specific endonuclease subunit antibody, crossover junction endonuclease MUS81 antibody, Restriction endonuclease, type II-like superfamily protein antibody, Mus81p antibody, Holliday junction resolvase subunit Mus81 antibody, MUS81 protein antibody, hypothetical protein antibody, mus81 antibody, MUS81 antibody, LOC725951 antibody, Mus81 antibody, CAALFM_C600540WA antibody

Background: MUS81 interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. It may be required in mitosis for the processing of stalled or collapsed replication forks.
Alias Symbols: FLJ21012, FLJ44872, SLX3
Protein Interaction Partner: SLX4, vpr, EME1, PLK1, FBXL5, SLX1A, WEE1, EME2, SUMO2, SLX1B, MUS81, CHEK2, TERT, TERF2,
Protein Size: 551

Molecular Weight: 61 kDa

Gene ID: 80198

NCBI Accession: NM_025128, NP_079404

UniProt: Q96NY9

Pathways: DNA Damage Repair