EIF2B5 antibody (N-Term)
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- Target See all EIF2B5 Antibodies
- EIF2B5 (Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa (EIF2B5))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Cow, Horse, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EIF2B5 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GVVVSRANKR SGAGPGGSGG GGARGAEEEP PPPLQAVLVA DSFDRRFFPI
- Predicted Reactivity
- Cow: 85%, Dog: 92%, Horse: 85%, Human: 100%, Rat: 85%
- Characteristics
- This is a rabbit polyclonal antibody against EIF2B5. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product EIF2B5 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 721 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Stoichiometry of the eIF2B complex is maintained by mutual stabilization of subunits." in: The Biochemical journal, Vol. 473, Issue 5, pp. 571-80, (2016) (PubMed).
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Stoichiometry of the eIF2B complex is maintained by mutual stabilization of subunits." in: The Biochemical journal, Vol. 473, Issue 5, pp. 571-80, (2016) (PubMed).
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- Target
- EIF2B5 (Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa (EIF2B5))
- Alternative Name
- EIF2B5 (EIF2B5 Products)
- Synonyms
- EIF2B5 antibody, F19I3.20 antibody, F19I3_20 antibody, F14P3.8 antibody, F14P3_8 antibody, AO090003000364 antibody, C81315 antibody, CACH antibody, CLE antibody, EIF-2B antibody, EIF2Bepsilon antibody, LVWM antibody, eukaryotic translation initiation factor 2B subunit epsilon antibody, eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa antibody, Trimeric LpxA-like enzyme antibody, translation initiation factor eif-2b epsilon subunit antibody, translation initiation factor eIF-2B epsilon subunit antibody, Translation initiation factor eIF-2B epsilon subunit, putative antibody, eukaryotic translation initiation factor 2B, subunit 5 epsilon antibody, EIF2B5 antibody, AT2G34970 antibody, AT3G02270 antibody, AOR_1_624154 antibody, CTRG_05484 antibody, PAAG_05066 antibody, CGB_A5380C antibody, TERG_01115 antibody, Eif2b5 antibody
- Background
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This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
Alias Symbols: CACH, CLE, EIF-2B, EIF2Bepsilon, LVWM
Protein Interaction Partner: UBC, EGFR, EIF2B2, EIF2B3, EIF2B4, APP, CHMP2A, GSK3A, GSK3B, EIF2S2, CSNK1A1, CSNK2A2, CSNK2A1, EIF2B1,
Protein Size: 721 - Molecular Weight
- 79 kDa
- Gene ID
- 8893
- NCBI Accession
- NM_003907, NP_003898
- UniProt
- Q13144
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