FMO2 antibody (N-Term)

Catalog No. ABIN2788732

Product Details anti-FMO2 Antibody

Target: FMO2 (Flavin Containing Monooxygenase 2 (Non-Functional) (FMO2))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FMO2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KYIQFQTTVL SVRKCPDFSS SGQWKVVTQS NGKEQSAVFD AVMVCSGHHI

Predicted Reactivity: Cow: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 85%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FMO2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FMO2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 471 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FMO2

Target: FMO2 (Flavin Containing Monooxygenase 2 (Non-Functional) (FMO2))

Alternative Name: FMO2 (FMO2 Products)

Synonyms: FMO 1B1 antibody, FMO 2 antibody, FMO1B1 antibody, 2310008D08Rik antibody, 2310042I22Rik antibody, AW107733 antibody, MGC68715 antibody, FMO4 antibody, FMO2 antibody, flavin containing monooxygenase 2 antibody, flavin containing monooxygenase 2 L homeolog antibody, FMO2 antibody, Fmo2 antibody, fmo2.L antibody

Background: The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.
Alias Symbols: FLJ40826, FMO1B1
Protein Size: 471

Molecular Weight: 54 kDa

Gene ID: 2327

NCBI Accession: NM_001460, NP_001451

UniProt: Q99518