UNG antibody (C-Term)

Catalog No. ABIN2788718

Product Details anti-UNG Antibody

Target: UNG (Uracil-DNA Glycosylase (UNG))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNG antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GWAKQGVLLL NAVLTVRAHQ ANSHKERGWE QFTDAVVSWL NQNSNGLVFL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%, Yeast: 79%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against UNG. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 313 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UNG

Target: UNG (Uracil-DNA Glycosylase (UNG))

Alternative Name: UNG (UNG Products)

Target Type: Viral Protein

Background: This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.
Alias Symbols: DGU, DKFZp781L1143, HIGM4, UDG, UNG1, UNG15, UNG2
Protein Interaction Partner: RPA3, RPA2, RPA1, vpr, SEZ6L2, CAPN11, UBC, SMUG1, UBE2E2, THOP1, APP, POLB, HSPB1, VPRBP, DDB1, PCNA, PPM1D,
Protein Size: 313

Molecular Weight: 34 kDa

Gene ID: 7374

NCBI Accession: NM_080911, NP_550433

UniProt: P13051

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response