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KPNB1 antibody (N-Term)

KPNB1 Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2788708
  • Target See all KPNB1 Antibodies
    KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
    Binding Specificity
    • 15
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 45
    • 17
    • 16
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit
    Host
    • 42
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 43
    • 3
    Polyclonal
    Conjugate
    • 22
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KPNB1 antibody is un-conjugated
    Application
    • 34
    • 13
    • 13
    • 11
    • 10
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    EHMKESTLEA IGYICQDIDP EQLQDKSNEI LTAIIQGMRK EEPSNNVKLA
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against KPNB1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product KPNB1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 876 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
    Alternative Name
    KPNB1 (KPNB1 Products)
    Synonyms
    Afu1g15720 antibody, AO090005001133 antibody, imb1 antibody, impnb antibody, ipo1 antibody, ipob antibody, ntf97 antibody, IMB1 antibody, IPO1 antibody, IPOB antibody, Impnb antibody, NTF97 antibody, AA409963 antibody, importin beta-1 subunit antibody, Importin beta-1 subunit antibody, karyopherin (importin) beta 1 L homeolog antibody, importin beta 1 antibody, karyopherin subunit beta 1 antibody, karyopherin (importin) beta 1 antibody, AFUA_1G15720 antibody, AOR_1_1974174 antibody, Bm1_57540 antibody, PMAA_065830 antibody, AFLA_083750 antibody, TSTA_085870 antibody, BDBG_07509 antibody, MCYG_00039 antibody, kpnb1.L antibody, LOC100533387 antibody, KPNB1 antibody, Kpnb1 antibody
    Background
    Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
    Alias Symbols: IMB1, IPO1, IPOB, Impnb, MGC2155, MGC2156, MGC2157, NTF97
    Protein Interaction Partner: HUWE1, UBC, FUS, SUMO2, SUMO3, STAU1, MDM2, EED, rev, CUL2, NLK, FBXO6, DYRK1B, CLK3, CDK11A, EGFR, SAMHD1, UBD, PTMA, ADRB2, RASSF5, AICDA, UBL4A, VCAM1, TAF10, NOS2, SMAD2, TAF8, TAF3, ITGA4, FN1, ERBB2, CFTR, YWHAE, SMURF1, ECT2, BARD1, MDC1, TP53BP1,
    Protein Size: 876
    Molecular Weight
    96 kDa
    Gene ID
    3837
    NCBI Accession
    NM_002265, NP_002256
    UniProt
    Q14974
    Pathways
    Protein targeting to Nucleus
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