Lipase A antibody (N-Term)

Catalog No. ABIN2788678

Product Details anti-Lipase A Antibody

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Binding Specificity: N-Term

Reactivity: Human, Rat, Horse, Pig, Cow, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lipase A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SYWGFPSEEY LVETEDGYIL CLNRIPHGRK NHSDKGPKPV VFLQHGLLAD

Predicted Reactivity: Cow: 93%, Horse: 86%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 86%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against LIPA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LIPA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 399 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Lipase A

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Alternative Name: LIPA (LIPA Products)

Synonyms: cesd antibody, lal antibody, LIPA antibody, CESD antibody, LAL antibody, Chole antibody, Chole2 antibody, Lip1 antibody, AA960673 antibody, Lal antibody, Lip-1 antibody, lipase A, lysosomal acid type antibody, lipase A, lysosomal acid, cholesterol esterase antibody, lipase A, lysosomal acid, cholesterol esterase L homeolog antibody, lysosomal acid lipase A antibody, LIPA antibody, lipa antibody, lipa.L antibody, Lipa antibody

Background: This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: CESD, LAL
Protein Interaction Partner: ELAVL1, UBC,
Protein Size: 399

Molecular Weight: 43 kDa

Gene ID: 3988

NCBI Accession: NM_000235, NP_000226

UniProt: P38571