Hexokinase 1 antibody (Middle Region)
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- Target See all Hexokinase 1 (HK1) Antibodies
- Hexokinase 1 (HK1)
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Horse, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Hexokinase 1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ILVKMAKEGL LFEGRITPEL LTRGKFNTSD VSAIEKNKEG LHNAKEILTR
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 77%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against HK1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human HK1
- Top Product
- Discover our top product HK1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 921 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Hexokinase 1 (HK1)
- Alternative Name
- HK1 (HK1 Products)
- Synonyms
- HK1-ta antibody, HK1-tb antibody, HK1-tc antibody, HKD antibody, HKI antibody, HMSNR antibody, HXK1 antibody, Hexokinase antibody, hk1 antibody, HEX antibody, HEX-1 antibody, HK antibody, ARABIDOPSIS THALIANA HEXOKINASE 1 antibody, ATHXK1 antibody, F19B15.160 antibody, F19B15_160 antibody, GIN2 antibody, GLUCOSE INSENSITIVE 2 antibody, HEXOKINASE antibody, hexokinase 1 antibody, im:7148527 antibody, wu:fc09d08 antibody, wu:fc16e02 antibody, wu:fc21e02 antibody, wu:fq14b11 antibody, zgc:55790 antibody, zgc:77618 antibody, hexokinase-1 antibody, HK1 antibody, BB404130 antibody, Hk-1 antibody, Hk1-s antibody, dea antibody, mHk1-s antibody, HEXOKIN antibody, Hxk1 antibody, NtHxK1 antibody, NtHxk antibody, hexokinase antibody, StHK1 antibody, hxk antibody, hk1-A antibody, hexokinase 1 antibody, hexokinase-1 antibody, Hexokinase 1 antibody, hexokinase 1, putative antibody, hexokinase 1 L homeolog antibody, HK1 antibody, hk1 antibody, LOC100136279 antibody, Hex1 antibody, HXK1 antibody, Hk1 antibody, TA19800 antibody, hxk1 antibody, LOC107797523 antibody, LOC102604144 antibody, hk1.L antibody
- Background
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Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
Alias Symbols: HK1-ta, HK1-tb, HK1-tc, HKI, HXK1
Protein Interaction Partner: SUMO2, SUMO3, STAU1, UBC, EGFR, SUMO1, NEDD8, MDM2, WDR61, UBA5, PARP6, NSFL1C, ARFGAP1, UBXN1, TWF2, FKBP9, PDCD10, PROSC, PLAA, GTF3C4, TUFM, TUBB2A, SGTA, RARS, PCNA, HEXB, HEXA, CAPN2, ASL, AHCY, PARK2, ATF2, VDAC1, LIG4, APP, AKT1, CDK2, SIRT7, ICT1,
Protein Size: 921 - Molecular Weight
- 103 kDa
- Gene ID
- 3098
- NCBI Accession
- NM_033498, NP_277033
- UniProt
- P19367
- Pathways
- Carbohydrate Homeostasis, Warburg Effect
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