PIGC antibody (C-Term)

Catalog No. ABIN2788604

Product Details anti-PIGC Antibody

Target: PIGC (Phosphatidylinositol Glycan C (PIGC))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio), Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIGC antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AVGAVLFALL LMSISCLCPF YLIRLQLFKE NIHGPWDEAE IKEDLSRFLS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against PIGC. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PIGC

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 297 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PIGC

Target: PIGC (Phosphatidylinositol Glycan C (PIGC))

Alternative Name: PIGC (PIGC Products)

Synonyms: GPI2 antibody, 3110030E07Rik antibody, AW212108 antibody, phosphatidylinositol glycan anchor biosynthesis class C antibody, phosphatidylinositol glycan anchor biosynthesis, class C antibody, PIGC antibody, Pigc antibody

Background: This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum.
Alias Symbols: GPI2, MGC2049
Protein Interaction Partner: KLF10, DPM2, ZHX1, PIGQ,
Protein Size: 297

Molecular Weight: 33 kDa

Gene ID: 5279

NCBI Accession: NM_002642, NP_002633

UniProt: Q92535

Pathways: Inositol Metabolic Process