MRPL45 antibody (C-Term)
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- Target See all MRPL45 Antibodies
- MRPL45 (Mitochondrial Ribosomal Protein L45 (MRPL45))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MRPL45 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- YGSWRMHTKI VPPWAPPKQP ILKTVMIPGP QLKPEEEYEE AQGEAQKPQL
- Predicted Reactivity
- Cow: 75%, Human: 100%, Mouse: 91%, Rat: 82%, Zebrafish: 75%
- Characteristics
- This is a rabbit polyclonal antibody against MRPL45. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human MRPL45
- Top Product
- Discover our top product MRPL45 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 306 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Human G-proteins, ObgH1 and Mtg1, associate with the large mitochondrial ribosome subunit and are involved in translation and assembly of respiratory complexes." in: Nucleic acids research, Vol. 41, Issue 6, pp. 3713-22, (2013) (PubMed).
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Human G-proteins, ObgH1 and Mtg1, associate with the large mitochondrial ribosome subunit and are involved in translation and assembly of respiratory complexes." in: Nucleic acids research, Vol. 41, Issue 6, pp. 3713-22, (2013) (PubMed).
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- Target
- MRPL45 (Mitochondrial Ribosomal Protein L45 (MRPL45))
- Alternative Name
- MRPL45 (MRPL45 Products)
- Synonyms
- L45mt antibody, MRP-L45 antibody, 2600005P05Rik antibody, AU043542 antibody, R75241 antibody, mrlp45 antibody, mitochondrial ribosomal protein L45 antibody, mitochondrial ribosomal protein L45 L homeolog antibody, Mrpl45 antibody, MRPL45 antibody, mrpl45.L antibody
- Background
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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q.
Alias Symbols: MGC11321, L45mt, MRP-L45
Protein Interaction Partner: TRIM23, UBC, C1QBP, TMEM177, MRPL24, MARCKSL1, MRPL9, MRPL11, MRPL32, MRPL38, MRPL47, SYNJ2BP, MRPL50, MRPL51, MRPL37, MRPL15, MRPL13, ZC3H4, HNRNPR, MRPL19, SDHB, ILF3, CUL3, ICT1, KBTBD7, G3BP1,
Protein Size: 306 - Molecular Weight
- 35 kDa
- Gene ID
- 84311
- NCBI Accession
- NM_032351, NP_115727
- UniProt
- Q9BRJ2
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