MARCKS antibody (C-Term)
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- Target See all MARCKS Antibodies
- MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
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Binding Specificity
- C-Term
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Reactivity
- Human, Cow, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MARCKS antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- EEGAAGGDPQ EAKPQEAAVA PEKPPASDET KAAEEPSKVE EKKAEEAGAS
- Predicted Reactivity
- Cow: 93%, Human: 100%, Rabbit: 79%
- Characteristics
- This is a rabbit polyclonal antibody against MARCKS. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human MARCKS
- Top Product
- Discover our top product MARCKS Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 332 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
- Alternative Name
- MARCKS (MARCKS Products)
- Synonyms
- 80K-L antibody, MACS antibody, PKCSL antibody, PRKCSL antibody, KINC antibody, Macs antibody, marcks antibody, MGC89127 antibody, MARCKS antibody, macs antibody, wu:fb55c06 antibody, wu:fb92d04 antibody, wu:fc19b04 antibody, wu:fc44a10 antibody, zgc:110235 antibody, fc34g03 antibody, fc38c06 antibody, wu:fc34g03 antibody, wu:fc38c06 antibody, zgc:109978 antibody, myristoylated alanine rich protein kinase C substrate antibody, myristoylated alanine-rich protein kinase C substrate antibody, methyl binding domain106 antibody, myristoylated alanine-rich protein kinase C substrate b antibody, myristoylated alanine-rich protein kinase C substrate S homeolog antibody, myristoylated alanine-rich protein kinase C substrate a antibody, MARCKS antibody, Marcks antibody, marcks antibody, mbd106 antibody, marcksb antibody, marcks.S antibody, marcksa antibody
- Background
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The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
Alias Symbols: 80K-L, FLJ14368, FLJ90045, MACS, PKCSL, PRKCSL
Protein Interaction Partner: UBC, TUBGCP3, UBQLN2, RPA2, PRKACA, PARK2, PKN1, PRKCB, HCVgp1, ATF2, PRKCZ, HSP90AA1, HNRNPU, DFFB, DBN1, SPP1, CDK4, CDK2, CDK1, CCNE1, ELAVL1, EBNA-LP, Mapk13, TOB1, PRKCA, NMT1, CTSB, CALM3, CALM2,
Protein Size: 332 - Molecular Weight
- 31 kDa
- Gene ID
- 4082
- NCBI Accession
- NM_002356, NP_002347
- UniProt
- P29966
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