MAP4 antibody (N-Term)
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- Target See all MAP4 Antibodies
- MAP4 (Microtubule-Associated Protein 4 (MAP4))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAP4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- LKETERASPI KMDLAPSKDM GPPKENKKET ERASPIKMDL APSKDMGPPK
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against MAP4. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4
- Top Product
- Discover our top product MAP4 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1152 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MAP4 (Microtubule-Associated Protein 4 (MAP4))
- Alternative Name
- MAP4 (MAP4 Products)
- Synonyms
- XMAP4 antibody, mtap4 antibody, AA407148 antibody, MAP-4 antibody, Mtap-4 antibody, Mtap4 antibody, microtubule associated protein 4 antibody, microtubule associated protein 4 L homeolog antibody, microtubule-associated protein 4 antibody, MAP4 antibody, map4.L antibody, Map4 antibody
- Background
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MAP4 is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression.
Alias Symbols: DKFZp779A1753, MGC8617
Protein Interaction Partner: UBC, LGR4, RPA3, RPA2, RPA1, LSM8, WDHD1, HNRNPR, PDCD6, PPP4R1, MTA2, POLR2C, POLR2A, IARS, HNRNPF, EIF2S1, CSTF2, COG7, TARDBP, BAG3, ERBB2IP, SNTA1, LDLR, IL7R, FN1, TRAF3IP1, RPS20, GRK5, EPS15, AP2M1, USP21, CUL4A, POT1, ISG15, TERF1, SIRT7, SH3KBP1,
Protein Size: 1152 - Molecular Weight
- 121 kDa
- Gene ID
- 4134
- NCBI Accession
- NM_002375, NP_002366
- UniProt
- P27816
- Pathways
- p53 Signaling, Microtubule Dynamics
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