DOK4 antibody (N-Term)

Catalog No. ABIN2788379

Product Details anti-DOK4 Antibody

Target: DOK4 (Docking Protein 4 (DOK4))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GPQRLEKYPD EKSVCLRGCP KVTEISNVKC VTRLPKETKR QAVAIIFTDD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against DOK4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DOK4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 326 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DOK4

Target: DOK4 (Docking Protein 4 (DOK4))

Alternative Name: DOK4 (DOK4 Products)

Synonyms: DOK4 antibody, docking protein 4 antibody, DOK4 antibody, Dok4 antibody

Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway
Alias Symbols: FLJ10488
Protein Interaction Partner: BAG3, ERBB2, EGFR, ELAVL1, TEK, SRC, CRK, RET, INSR, IGF1R, RASA1, FYN,
Protein Size: 326

Molecular Weight: 36 kDa

Gene ID: 55715

NCBI Accession: NM_018110, NP_060580

UniProt: Q8TEW6