CD55 antibody (Middle Region)
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- Target See all CD55 Antibodies
- CD55 (Complement Decay-Accelerating Factor (CD55))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Dog, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CD55 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PGYRREPSLS PKLTCLQNLK WSTAVEFCKK KSCPNPGEIR NGQIDVPGGI
- Predicted Reactivity
- Dog: 79%, Horse: 79%, Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against CD55. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CD55
- Top Product
- Discover our top product CD55 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 381 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CD55 (Complement Decay-Accelerating Factor (CD55))
- Alternative Name
- CD55 (CD55 Products)
- Synonyms
- CR antibody, CROM antibody, DAF antibody, TC antibody, Daf antibody, Daf-GPI antibody, Daf1 antibody, GPI-DAF antibody, CD55 molecule (Cromer blood group) antibody, CD55 molecule, decay accelerating factor for complement antibody, CD55 antibody, Cd55 antibody
- Background
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This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF), binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels.
Alias Symbols: CR, CROM, DAF, TC
Protein Interaction Partner: UBC, NDUFB7, NDUFS7, TIMM50, INF2, SYNJ2BP, PTCD3, PTRH2, MRPL4, SLC25A24, RAB31, ZMPSTE24, PICALM, SLC12A4, SLC2A1, S100A10, MPV17, MAN2A1, GNAI3, ATP6V1E1, GPLD1, CD97, CD14, LCK, FYN, CD55, CR1,
Protein Size: 381 - Molecular Weight
- 41 kDa
- Gene ID
- 1604
- NCBI Accession
- NM_000574, NP_000565
- UniProt
- P08174
- Pathways
- Complement System, Regulation of Leukocyte Mediated Immunity
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