SPANXC antibody (N-Term)

Catalog No. ABIN2788255

Product Details anti-SPANXC Antibody

Target: SPANXC (SPANX Family, Member C (SPANXC))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPANXC antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EVNETMPETP TGDSDPQPAP KKMKTSESST ILVVRYRRNV KRTSPEELLN

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SPANXC. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 97 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPANXC

Target: SPANXC (SPANX Family, Member C (SPANXC))

Alternative Name: SPANXC (SPANXC Products)

Synonyms: C antibody, CT11.3 antibody, CTp11 antibody, SPANX-C antibody, SPANX family member C antibody, SPANXC antibody

Background: Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy.
Alias Symbols: C, CT11.3, CTp11, SPANX-C
Protein Interaction Partner: SETBP1,
Protein Size: 97

Molecular Weight: 11 kDa

Gene ID: 64663

NCBI Accession: NM_022661, NP_073152

UniProt: Q9NY87