Gastrin-Releasing Peptide antibody (C-Term)
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- Target See all Gastrin-Releasing Peptide (GRP) Antibodies
- Gastrin-Releasing Peptide (GRP)
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Gastrin-Releasing Peptide antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ENRNHQPPQP KALGNQQPSW DSEDSSNFKD VGSKGKGSQR EGRNPQLNQQ
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against GRP. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product GRP Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 141 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Gastrin-Releasing Peptide (GRP)
- Alternative Name
- GRP (GRP Products)
- Synonyms
- BLP antibody, GRP antibody, BN antibody, GRP-10 antibody, preproGRP antibody, proGRP antibody, gastrin releasing peptide antibody, Grp antibody, GRP antibody
- Background
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This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: BN, GRP-10, preproGRP, proGRP
Protein Interaction Partner: MEP1B, MEP1A, GRPR, DPP4,
Protein Size: 141 - Molecular Weight
- 15 kDa
- Gene ID
- 2922
- NCBI Accession
- NM_001012512, NP_001012530
- Pathways
- Peptide Hormone Metabolism, Hormone Activity
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