CORT antibody (N-Term)

Catalog No. ABIN2788111

Product Details anti-CORT Antibody

Target: CORT (Cortistatin (CORT))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CORT antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MPLSPGLLLL LLSGATATAA LPLEGGPTGR DSEHMQEAAG IRKSSLLTFL

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CORT. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CORT

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 155 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CORT

Target: CORT (Cortistatin (CORT))

Alternative Name: CORT (CORT Products)

Synonyms: CST-14 antibody, CST-17 antibody, CST-29 antibody, CST antibody, PCST antibody, cortistatin antibody, CORT antibody, Cort antibody

Background: This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739.
Alias Symbols: CST-14, CST-17, CST-29
Protein Interaction Partner: MRGPRX2, GHSR, SSTR5, SSTR4, SSTR3, SSTR2, SSTR1,
Protein Size: 155

Molecular Weight: 2 kDa

Gene ID: 1325

NCBI Accession: NM_001302, NP_001293

UniProt: O00230