ERC1 antibody (C-Term)

Catalog No. ABIN2788091

Product Details anti-ERC1 Antibody

Target: ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1 (ERC1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERC1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KLMADNYEDD HFKSSHSNQT NHKPSPDQII QPLLELDQNR SKLKLYIGHL

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against ERC1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ERC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1116 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ERC1

Target: ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1 (ERC1))

Alternative Name: ERC1 (ERC1 Products)

Background: The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10,12)(q11,p13). Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: Cast2, ELKS, FLJ31750, KIAA1081, MGC12974, RAB6IP2
Protein Interaction Partner: UBC, LATS2, CDK20, CDK19, MAPK4, STK4, PAN2, MYC, ATP6V0D1, NCBP1, APP, ERC2, WDR4, CUL3, IKBKG, NFKBIA, IKBKB, CHUK, SH3KBP1, ITSN2, RAD23A, YWHAG, MAP3K7, XIAP, KBTBD7, RAB6B, PPFIA1, RIMS1, ERC1, RAB6A, TWF2,
Protein Size: 1116

Molecular Weight: 128 kDa

Gene ID: 23085

NCBI Accession: NM_178040, NP_829884

UniProt: Q8IUD2

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection